Since 2000, global investment in malaria prevention and control has successfully prevented more than 2 billion cases and nearly 13 million deaths. However, as communities and prevention and control programs are recently facing the negative impact of funding cuts, the process of malaria elimination is encountering systematic threats. The 2025 funding cut plan for malaria prevention and control programs will expose millions of people to additional life risks, which may reverse the decades-long prevention and control achievements made through long-term investment by international partners. Dr. Daniel Ngamije, Director of the WHO Global Malaria Programme, warned: "Historical experience reveals that slack in malaria prevention and control will lead to catastrophic consequences. After the termination of the Global Malaria Eradication Programme in 1969, cases and mortality immediately rebounded. It took the international community nearly 30 years to rebuild the consensus and action framework for prevention and control." Although some malaria programs have resumed funding support, the critical gaps caused by service disruptions still exist. If the rapid coverage of prevention and treatment services for high-risk groups cannot be achieved, the consequences will be fatal.